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VIM

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This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
  • CAR Vector Products

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    CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
    XS-1222-ZP218 VIM (CD44 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human VIM-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
    XS-1222-ZP1618 VIM (CD44 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human VIM-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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