ActivatorPep™ CMV pp65 Recombinant Protein-S (CA-LX029)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Product Name
ActivatorPep™ CMV pp65 Recombinant Protein-S

Cat. No.
CA-LX029

Product Summary
Creative Biolabs provides an extensive cell activation reagents including Expansion Kits and Activator peptides for global custom, which are suitable to many applications, such as in vitro stimulation antigen-specific cells. CMV pp65 Recombinant Protein is designed for the in vitro stimulation of pp65-specific CD4+ and CD8+ T cells. Which can be used for in vitro stimulation of pp65-specific CD4+ and CD8+ T cells..

Background Information
Human cytomegalovirus (CMV, HCMV) is a member of the herpes virus group. Between 50% and 85% of human adults are infected with CMV. Once infected, the virus persists in the organism. In healthy individuals, the infection is asymptomatic, but in immunocompromised patients CMV can cause severe disease. The pp65 protein (65 kDa lower matrix phosphoprotein), also known as glycoprotein 64 or UL83, is a virion tegument protein and the main component of the enveloped subviral particle. pp65 is an immunodominant target of CD4+ as well as CD8+ T cell responses to CMV. pp65-specific T cells predominantly produce cytokines such as IFN-γ, IL-2, and TNF-α.

Applications
Stimulation Reagents

Cross-reactivity
No significant cross-reactivity was observed among analytes in this panel.

Species Reactivity
Human

Purity or Quality Grade
Research Grade

Downstream Application
Pulsing of antigen-presenting cells for research;
Detection and analysis of antigen-specific CD4+ and CD8+ effector/memory T cells in PBMCs;

Product Size
for stimulation of up to 2×108 total cells

Shipping Condition
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage Conditions
Store at -20°C.

Shelf life
> 6 Months from date of receipt under proper storage condition.

Product Use Statement
For research use only, not for diagnostic or therapeutic use.

Product Features
Efficient expansion and increased survival rate of Ag-specific T cells;
Provides a gentle activation stimulus that maintains high viability of activated and expanded T cells;

Research Category
Immunology

Panel Type
Stimulation for CD4+ and CD8+ T cells

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

ActivatorPep™ CMV pp65 Recombinant Protein-S (CA-LX029)

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