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Anti-CTAG1A (SLLMWITQC) TCR, pMSGV1(TCR-L077)

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The vector of anti-NY-ESO-1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human NY-ESO-1. The T cells are genetically modified through transduction with a retroviral vector expressing NY-ESO-1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.

Details

Target
NY-ESO-1
Target Species
Human
Epitope
SLLMWITQC
Format
Non-modified TCR
HLA
HLA-A2
Targeting Diseases
Melanoma
Vector Name
pMSGV1
Vector Length
6700-8070bp
Vector Type
retroviral vector
Antibody Host
Mouse

Target

Gene Name
cancer/testis antigen 1A
Official Symbol
CTAG1A
Gene ID
246100
UniProt ID
P78358
Synonyms
OVA; Ovalbumin; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Food allergy
Introduction
The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

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