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anti-HBV (FLLTRILTI) TCR, pCDTCR1 (TCR-L043Z)

The vector of anti-HBV T cell receptor (TCR) is constructed for the engineering of T cell to target HBV. The T cells are genetically modified through transduction with a retroviral vector expressing HBV-specific T cell receptor. And the vector product was designed for the treatment of Hepatitis B encoding at least one virus (HBV) and hepatocellular carcinoma (HCC) .

Details

  • Target
  • HBV
  • Target Species
  • HBV
  • Epitope
  • FLLTRILTI
  • Format
  • Cysteine-modified
  • HLA
  • HLA-A0201
  • Targeting Diseases
  • Hepatitis B encoding at least one virus (HBV) and hepatocellular carcinoma (HCC)
  • Vector Name
  • pCDTCR1
  • Vector Length
  • 8kb
  • Vector Type
  • Lentiviral
  • Antibody Host
  • Human

Target

  • Gene Name
  • Hepatitis B virus
  • Official Symbol
  • HBV
  • Synonyms
  • HbsAg; HBV; Major surface antigen; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Hepatitis B encoding at least one virus; HBV; hepatocellular carcinoma; HCC
  • Introduction
  • epatitis B virus, abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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