Name: Anti-Human GP100 (R6C12) TCR (HLA-A*0201/ITDQVPFSV) Lentivirus Packaging Kit
SKU: XS-0622-YF185
Rating: 5 (1 reviews)

Solutions
- Solutions
  Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
  EXPLORE MORE Highlights
  - TCR-T Development Solutions
  - CAR-T Development Solutions
Products
- Products
  We focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
  EXPLORE MORE Highlights
  - CAR/TCR Development Kits
  - Oncology
CDMO
- CDMO
  The advent of Chimeric Antigen Receptor T-cell (CAR-T) therapies has revolutionized the field of oncology, providing new avenues for treating various forms of cancer. Our 20 years of experience in the biotechnology sector have equipped us with the expertise and technological capabilities to support the entire lifecycle of CAR-T products, from early development to commercialization.
  EXPLORE MORE
Platforms
- Platforms
  To accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
  EXPLORE MORE Highlights
  - CAR Technology
  - TCR Technology
Resources
- Resources
  Use the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
  EXPLORE MORE Highlights
  - Flyers
  - Newsletter
Company
- - Distributors
  - About Us
  - Contact Us
  - Careers
  - Events
- About Creative Biolabs
  Get a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
  EXPLORE MORE

Product Search Services Search Keyword Search

Description

Target
GP100

Components
This kit contains a TCR lentiviral vector, packaging vectors, TCR detection reagent, and 293 cells.
1. A TCR lentiviral vector
• Anti-GP100 (R6C12) TCR plasmid
2. Three packaging vectors
• LentiArt™ pHelp1
• LentiArt™ pHelp2
• LentiArt™ pHelp3
3. TCR detection reagent
4. 293 cells

Size
10 reactions; 20 reactions; 50 reactions

Storage Conditions
For details of the storage requirements, please see the User Manual for instructions.

Applications
TCR lentivirus packaging; TCR lentivirus transfection; TCR-T cell development; TCR-T cell therapy.

TCR Vector

MHC Allele
HLA-A*0201

Peptide
ITDQVPFSV

Epitope
209-217

Vector Name
pCDCAR1

Vector Length
~8kb

Vector Type
Lentiviral vector

TCR Construction
TCR alpha-P2A-TCR beta

Target

Gene Name
PMEL

Full Name
premelanosome protein

scFv
R6C12

Host Species
Human

Target Species
Human

Gene ID
6490

Uniprot ID
P40967

Target Background
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.

Synonyms
P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E

Related Disease
Melanoma

Customer Reviews and Q&As

There are currently no customer reviews or questions for Anti-Human GP100 (R6C12) TCR (HLA-A*0201/ITDQVPFSV) Lentivirus Packaging Kit (XS-0622-YF185). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.