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anti-IAV (GILGFVFTL) TCR, pCDTCR1 (TCR-L054Z)

The vector of anti-IAV T cell receptor (TCR) is constructed for the engineering of T cell to target IAV. The T cells are genetically modified through transduction with a retroviral vector expressing IAV-specific T cell receptor. And the vector product was designed for the treatment of Influenza.

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Details

  • Target
  • IAV
  • Target Species
  • IAV
  • Epitope
  • GILGFVFTL
  • Format
  • Cysteine-modified
  • HLA
  • HLA-A0201
  • Targeting Diseases
  • Influenza
  • Vector Name
  • pCDTCR1
  • Vector Length
  • 8kb
  • Vector Type
  • Lentiviral
  • Antibody Host
  • Human

Target

  • Official Symbol
  • IAV
  • Introduction
  • The Orthomyxoviruses are a family of RNA viruses that includes six genera: Influenza virus A, Influenza
    virus B, Influenza virus C, Isavirus, Thogotovirus and Quaranjavirus. Influenza A and C infect multiple
    species, while influenza B almost exclusively infects humans. The first three genera contain viruses
    that cause influenza in vertebrates, including birds (see also avian influenza), humans, and other
    mammals. Isaviruses infect salmon; thogotoviruses infect vertebrates and invertebrates, such as
    mosquitoes and sea lice.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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