Anti-LMNA DNA-encoded mAb (DMAb), pVAX1 (DMAb-0107-YJ)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-LMNA DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

Add to Cart

Specifications

Target
LMNA

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
4000

UniProt ID
P02545

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-0107-YJ	12A-2F5	Mouse	Human	IgG1, κ	Synthetic peptide corresponding to amino acids 449-457 of human Lamin A + C [Accession#: NP_733821.1].
DMAb-0108-YJ	133A2	Mouse		IgG3	Clone 133A2 recognizes an epitope located between residues 598-611 of lamin A and therefore 133A2 reacts exclusively with lamin A.
DMAb-013-YC	1B7	Mouse	Human	IgG1
DMAb-416-YC	2G1	Mouse	Human	IgG1
DMAb-0111-YJ	2Q1131	Mouse		IgG1	Lamin purified from rat liver.
DMAb-0112-YJ	3D6-F4-B7	Mouse		IgG2a
DMAb-0113-YJ	3F6	Mouse	Human	IgG2b
DMAb-0880-CQ	4C11	Mouse		IgG2a
DMAb-1086-LY	4C4	Mouse		IgG1	Full length recombinant human Lamin A + C [UniProt# P02545].
DMAb-0892-CQ	4E7	Mouse		IgG1	The immunogen corresponding to human LMNA expressed in E. Coli.
DMAb-0117-YJ	5D12-C6-E9	Mouse	Human	IgG1
DMAb-0118-YJ	5H8-B4	Mouse	Human	IgG1
DMAb-0119-YJ	636	Mouse		IgG2b
DMAb-0120-YJ	EM-11	Mouse		IgG2a	The Lamin C antibody recognizes lamin C an intermediate filament protein of the nuclear lamina.
DMAb-0121-YJ	JOL2	Mouse		IgG1
DMAb-0122-YJ	JoL3	Mouse	Human	IgG1
DMAb-0123-YJ	JOL4	Mouse	Human	IgG
DMAb-0124-YJ	JoL5	Mouse	Human	IgG2
DMAb-0125-YJ	mab636	Mouse		IgG2b	Porcine lamin preparation.
DMAb-0126-YJ	R27	Mouse		IgM
DMAb-0127-YJ	X167	Mouse		IgG1
DMAb-0168-YJ	X67	Mouse	Xenopus	IgG1	Lamin antibody was raised in mouse using Nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells) as the immunogen.

Customer Reviews and Q&As

There are currently no customer reviews or questions for Anti-LMNA DNA-encoded mAb (DMAb), pVAX1 (DMAb-0107-YJ). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-LMNA DNA-encoded mAb (DMAb), pVAX1 (DMAb-0107-YJ)

Specifications

Target

Customer Reviews and Q&As

Related Products

CAR Vector Products