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LMNA

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The nuclear lamina composed of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to function in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ107 Anti-LMNA (12A-2F5) h(41BB-CD3ζ) CAR, pCDCAR1 Human 12A-2F5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ108 Anti-LMNA (133A2) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Cattle, Dog 133A2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ109 Anti-LMNA (1B7) h(41BB-CD3ζ) CAR, pCDCAR1 Human 1B7 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ110 Anti-LMNA (2G1) h(41BB-CD3ζ) CAR, pCDCAR1 Human 2G1 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ111 Anti-LMNA (2Q1131) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle, Dog, Hamster, Human, Mouse, Rat, Sheep 2Q1131 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ119 Anti-LMNA (636) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle, Human, Pig 636 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ120 Anti-LMNA (EM-11) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse EM-11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ121 Anti-LMNA (JOL2) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Monkey JOL2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ122 Anti-LMNA (JoL3) h(41BB-CD3ζ) CAR, pCDCAR1 Human JoL3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ123 Anti-LMNA (JOL4) h(41BB-CD3ζ) CAR, pCDCAR1 Human JOL4 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ124 Anti-LMNA (JoL5) h(41BB-CD3ζ) CAR, pCDCAR1 Human JoL5 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ125 Anti-LMNA (mab636) h(41BB-CD3ζ) CAR, pCDCAR1 Human, Mouse, Pig, Rat, Cattle mab636 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ126 Anti-LMNA (R27) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle, Fish, Human, Mouse, Rat, Xenopus, Zebrafish R27 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ127 Anti-LMNA (X167) h(41BB-CD3ζ) CAR, pCDCAR1 Cattle, Fish, Human, Xenopus X167 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ168 Anti-lmna (X67) h(41BB-CD3ζ) CAR, pCDCAR1 Xenopus X67 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ607 Anti-LMNA (12A-2F5) h(CD28-CD3ζ) CAR, pCDCAR1 Human 12A-2F5 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ608 Anti-LMNA (133A2) h(CD28-CD3ζ) CAR, pCDCAR1 Human, Mouse, Rat, Cattle, Dog 133A2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ609 Anti-LMNA (1B7) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1B7 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ610 Anti-LMNA (2G1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 2G1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ611 Anti-LMNA (2Q1131) h(CD28-CD3ζ) CAR, pCDCAR1 Cattle, Dog, Hamster, Human, Mouse, Rat, Sheep 2Q1131 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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