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Anti-MLANA [27–35] TCR, pLXSN (TCR-L069)

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-MART-1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human MART-1 (MLANA). The T cells are genetically modified through transduction with a retroviral vector expressing MART-1 (MLANA)-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.

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Details

  • Target
  • MART-1 (MLANA)
  • Target Species
  • Human
  • Epitope
  • MART-1[27– 35]
  • Format
  • Non-modified TCR
  • Allele
  • HLA-A2
  • Targeting Diseases
  • Melanoma
  • Vector Name
  • pLXSN
  • Vector Length
  • 6714-6688bp
  • Vector Type
  • retroviral vector
  • Host Species
  • Human

Target

  • Official Symbol
  • MLANA
  • Introduction
  • Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the
    expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the
    formation of stage II melanosomes.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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