Artificial CD8+ T Cell Stimulator (HLA-A2 Restricted, 5 μm) (XS-0425-WR32)

Name: Artificial CD8+ T Cell Stimulator (HLA-A2 Restricted, 5 μm)
SKU: XS-0425-WR32
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is a fluid lipid bilayer coated onto cytometry-compatible silica microbeads-based artificial T cell stimulator. It can effectively activate and stimulate human CD8+ T cells.

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Application
Human CD8+ T cell stimulation.

Matric (Cells/Biomaterials)
A fluid lipid bilayer coated onto cytometry-compatible silica microbeads

HLA Restriction
HLA-A2

Diameter
5 μm

Form
Acellular Artificial T Cell Stimulator

Intensity of Existence
1:4 (anti-CD3:anti-CD28)

Target Cell
CD8+ T cell

Target Species
Human

Surface Moieties
Anti-CD3-biotin and Anti-CD28-biotin

Transduction Method
Surface conjugation and encapsulation are used for protein incorporation

Co-stimulating Signal
Anti-CD28-biotin

Antigen
HIV-1 derived peptides (SL9 peptide (pSL9:SLFNTVATL), and other HIV peptides)

Antigen Loading
Biotinylated anti-CD3 and/or anti-CD28 agonist antibodies are added to the lipid bilayer-coated silica microbeads via streptavidin-biotin linkage.

Antigen Presentation Pathway
The signals needed for T cell activation are conjugated directly to the artificial T cell stimulators.

Culture Medium/Storage solution
HBS-BSA 1% buffer

Format
1 EA

Shipping
Ice bags

Handling advice
Preserve product functionality and integrity by employing strict aseptic handling and adhering to the manufacturer's storage, preparation, and cell culture specifications.

Storage
Store at 4°С.

Highlights
Efficient T-cell Activation; Controlled Activation; Off-the-Shelf Availability

Quality Control
This product has been tested for transduced molecule expression and effective CD8+ T cell activation.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Artificial CD8+ T Cell Stimulator (HLA-A2 Restricted, 5 μm) (XS-0425-WR32)

Customer Reviews and Q&As

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