Artificial CD8+ T Cell Stimulator (HLA Class II Restricted, Acellular) (XS-0425-WR3)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is an NIH/3T3 cell line-based artificial T cell stimulator, transduced with single HLA class II molecule, CD80, CD54, and CD58 through the retroviral expression system. It can effectively activate and stimulate mouse CD8+ T cells.

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  • Application
  • Mouse CD8+ T cell stimulation.
  • Matric (Cells/Biomaterials)
  • NIH/3T3 cell line
  • HLA Restriction
  • HLA class II
  • Diameter
  • Cell-level
  • Form
  • Cellular Artificial T Cell Stimulator
  • Target Cell
  • CD8+ T cell
  • Target Species
  • Mouse
  • Surface Moieties
  • CD54, CD58, CD80, and one HLA-II molecule
  • Transduction Method
  • Retroviral
  • Co-stimulating Signal
  • CD54, CD58, CD80
  • Antigen
  • Infectious antigens, Survivin, a tumor-associated antigen (TAA), anti-tumor or anti-viral antigens
  • Antigen Loading
  • Exogenous loading with peptides. Transduction with CD64 to improve uptake and presentation of whole protein antigens under immune complex forms.
  • Antigen Presentation Pathway
  • MHC-dependent presentation pathway
  • Format
  • 1 EA
  • Shipping
  • Dry ice
  • Handling advice
  • Avoid repeated freeze-thaw
  • Storage
  • Liquid nitrogen
  • Highlights
  • Efficient T-cell Activation; Controlled Activation; Off-the-Shelf Availability
  • Mycoplasma
  • Negative
  • Quality Control
  • This product has been tested for transduced molecule expression and effective CD8+ T cell activation.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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