The vector of anti-CEA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CEA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CEA antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of CEA positive cancers.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-LC368||Anti-CEACAM5 h(CD3ζ, CD80, 41BBL) Armoured CAR, pCDCAR1|
|CAR-MZ089||Anti-CEA (SCA431) h(OX40-CD3ζ) CAR, pCDCAR1|
|CAR-MZ145||Anti-CEA (F11-39) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC796||Lenti-CEA CAR (scFv-CD28-CD3ζ, SCA431) Viral Particle|
|VP-CAR-LC148||Lenti-CEA CAR (scFv-CD28-FcεRIγ, BW431/26) Viral Particle|
|VP-CAR-LC805||Lenti-CEA CAR (scFv-CD28-CD3ζ, MFE23) Viral Particle|
|VP-CAR-LC156||Lenti-CEA CAR (scFv-CD28-OX40-CD3ζ, BW431/26) Viral Particle|
|CAR-T-1-M314-2||Anti-CEA scFv h(CD28) CART, pCDCAR1|
|CAR-T-2-M314-BZ||Anti-CEA scFv h(41BB-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC763||Lenti-CEA CAR (scFv-CD3ζ-OX40, BW431/26) Viral Particle|
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