CellRapeutics™ CD19⁺ B Cells from Human Immunodeficiency Virus HIV Donor (XS-0426-XU3)

Name: CellRapeutics™ CD19+ B Cells from Human Immunodeficiency Virus HIV Donor
SKU: XS-0426-XU3
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is composed of B cells isolated from the peripheral blood of HIV-positive donors. These cells are indispensable for researchers focusing on humoral immunity under chronic viral stress, offering a high-quality model to study B cell exhaustion, hyperactivation, and the mechanisms of broadly neutralizing antibody development in a compromised host environment.

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Donor Information

Product Name
CellRapeutics™ CD19⁺ B Cells from Human Immunodeficiency Virus HIV Donor

Cat. No.
XS-0426-XU3

Donor Age
Young Adult, Middle-Aged

Donor Health
Confirmed positive for HIV-1 or HIV-2 infection. Donors are categorized based on their viral load and CD4⁺ T-cell counts, reflecting a compromised immune state and altered B-cell homeostasis.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Heparin or Acid Citrate Dextrose, formulated to stabilize fragile lymphocyte membranes and prevent premature cell lysis common in chronic viral infections during prolonged processing.

Additional Donor Information
Each lot features CD19⁺ B cells from HIV-seropositive donors. Comprehensive data include viral load, CD4⁺ T-cell counts, and duration of Antiretroviral Therapy, enabling researchers to investigate B-cell exhaustion and humoral immune dysfunction in chronic viral infection.

Clinical Profile
Current viral load, CD4⁺ T-cell count, duration of infection, and antiretroviral therapy history/status.

Additional Information

Medication History
Available upon request. Focuses on Antiretroviral Therapy history, including regimen duration, viral load suppression status, and any history of opportunistic infection prophylaxis.

Formulation
Cryopreserved in specialized freezing medium

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.

Storage
Upon arrival, immediately transfer the vial to the liquid nitrogen.

Shiping
Dry Ice

Handling Notes
Upon thawing, it is recommended to rapidly thaw the cells in a 37°C water bath, followed by the slow addition of pre-warmed culture medium to minimize osmotic shock.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
1E7 cells/vial, 2.5E7 cells/vial

Keywords
CellRapeutics™ CD19⁺ B Cells from Human Immunodeficiency Virus HIV Donor, CD19⁺ B Cells, Human Immunodeficiency Virus HIV

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

CellRapeutics™ CD19⁺ B Cells from Human Immunodeficiency Virus HIV Donor (XS-0426-XU3)

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CellRapeutics™ CD19+ B Cells from Human Immunodeficiency Virus HIV Donor (XS-0426-XU3)

Specific Inquiry

Donor Information

Additional Information

Case Studies

Customer Reviews and Q&As

Related Products

Control Cell Products

Immune Cell Products

Neutrophil Products

PBMC Products

T Cell Products

B Cell Products

Dendritic Cell Products

NK Cell Products

Stem Cell Products

CellRapeutics™ CD19⁺ B Cells from Human Immunodeficiency Virus HIV Donor (XS-0426-XU3)