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CellRapeutics™ CD19+ B Cells from Celiac Disease Donor (XS-0426-XU1)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product consists of high-purity CD19+ B Cells isolated from the peripheral blood mononuclear cells (PBMCs) of donors clinically diagnosed with Celiac Disease (CD). Cells are isolated using immunomagnetic separation (positive or negative selection) to ensure minimal activation and maximum viability.

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Donor Information

  • Product Name
  • CellRapeutics™ CD19+ B Cells from Celiac Disease Donor
  • Cat. No.
  • XS-0426-XU1
  • Donor Age
  • Young Adult, Middle-Aged
  • Donor Health
  • Clinically diagnosed with Celiac Disease exhibiting characteristic autoimmune profiles. Donors are screened and confirmed negative for major infectious diseases (e.g., HIV, HBV, HCV).
  • Ethnicity
  • Diverse backgrounds available.
  • Anticoagulant
  • Acid Citrate Dextrose or Heparin, optimized to maintain maximum cellular viability and functional metabolic state during leukapheresis and processing.
  • Additional Donor Information
  • Each lot features CD19+ B cells from donors with clinically confirmed Celiac Disease. Comprehensive profiles include demographic data (age, sex, ethnicity) alongside longitudinal medication and clinical histories, ensuring researchers can correlate B-cell phenotypes with specific gluten-free diet adherence and comorbidities.
  • Clinical Profile
  • Comprehensive history including year of diagnosis, documented autoimmune comorbidities, and known allergen sensitivities.

Additional Information

  • Medication History
  • Available upon request. Includes detailed documentation regarding adherence to a Gluten-Free Diet and history of immunomodulatory therapeutic interventions.
  • Formulation
  • Cryopreserved in specialized freezing medium
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.
  • Storage
  • Upon arrival, immediately transfer the vial to the liquid nitrogen.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Upon thawing, it is recommended to rapidly thaw the cells in a 37°C water bath, followed by the slow addition of pre-warmed culture medium to minimize osmotic shock.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • 1E7 cells/vial, 2.5E7 cells/vial
  • Keywords
  • CellRapeutics™ CD19+ B Cells from Celiac Disease Donor, CD19+ B Cells, Celiac Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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