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CellRapeutics™ Leukopak from Celiac Disease Donor (XS-0426-XU231)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This Leukopak provides a concentrated collection of peripheral blood mononuclear cells from donors with clinically confirmed Celiac Disease. The leucocyte profile is particularly enriched with gluten-reactive T-cell precursors and B-cell subsets primed for the production of anti-tissue transglutaminase antibodies. It serves as a high-yield source for studying the loss of oral tolerance and the systemic migration of gut-homing lymphocytes involved in gluten-sensitive enteropathy.

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Donor Information

  • Product Name
  • CellRapeutics™ Leukopak from Celiac Disease Donor
  • Cat. No.
  • XS-0426-XU231
  • Donor Age
  • Young Adult
  • Donor Health
  • Leukocytes exhibit sensitized profiles toward gluten peptides. The cell population reflects a gut-focused autoimmune bias with specific integrin expression patterns related to mucosal-associated lymphoid tissue.
  • Ethnicity
  • Diverse backgrounds available, predominantly Caucasian.
  • Anticoagulant
  • Acid Citrate Dextrose, specifically chosen to maintain the metabolic profile of gluten-reactive T cells and mucosal-homing lymphocytes.
  • Additional Donor Information
  • Each lot features a Leukopak from donors with Celiac disease. This bulk format allows for the isolation of rare gluten-specific T and B cell subsets and extensive HLA-typing analysis.
  • Clinical Profile
  • Diagnostic confirmation, adherence to gluten-free diet, and history of related malabsorption symptoms.

Additional Information

  • Medication History
  • Available upon request. Includes detailed documentation regarding adherence to a Gluten-Free Diet and history of immunomodulatory therapeutic interventions.
  • Formulation
  • Cryopreserved or Fresh options available.
  • Cell Purity
  • >90%
  • Cell Viability
  • >90%
  • Mycoplasma Testing
  • Negative
  • Sterility Testing
  • Negative
  • Genetic Stability Testing
  • The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.
  • Application
  • Drug Discovery, Immuno-oncology Research
  • Research Use Only
  • RUO
  • Quality Control
  • Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.
  • Storage
  • Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.
  • Shiping
  • Dry Ice
  • Handling Notes
  • Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.
  • Warnings
  • Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.
  • Size
  • Full Bag, Half Bag
  • Keywords
  • CellRapeutics™ Leukopak from Celiac Disease Donor, Leukopak, Celiac Disease

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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