CellRapeutics™ CD56⁺ NK Cells from Human Immunodeficiency Virus HIV Donor (XS-0426-XU296)

Name: CellRapeutics™ CD56+ NK Cells from Human Immunodeficiency Virus HIV Donor
SKU: XS-0426-XU296
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product consists of CD56⁺ NK cells isolated from HIV-positive donors, providing a specialized tool for studying the innate response to chronic viral infection. The population often exhibits phenotypic shifts. These cells are essential for research into Antibody-Dependent Cellular Cytotoxicity and the development of strategies to enhance NK-mediated clearance of the viral reservoir.

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Donor Information

Product Name
CellRapeutics™ CD56⁺ NK Cells from Human Immunodeficiency Virus HIV Donor

Cat. No.
XS-0426-XU296

Donor Age
Young Adult, Middle-Aged

Donor Health
NK cells exhibit signatures of chronic viral pressure and potential functional exhaustion. The population is marked by shifts in CD56 and CD56 subset ratios and characteristic alterations in KIR expression diversity.

Ethnicity
Diverse backgrounds available.

Anticoagulant
Acid Citrate Dextrose, selected to stabilize NK cell functional exhaustion markers and ensure maximal recovery of effector cells from immunodeficient peripheral blood environments.

Additional Donor Information
Each lot features CD56⁺ NK cells from HIV-positive donors. Profiles include viral load and ART status, supporting research into NK cell exhaustion and their potential in "shock and kill" therapeutic strategies.

Clinical Profile
Current viral load, CD4⁺ T-cell count history, duration of HIV infection, and history of Antiretroviral Therapy.

Additional Information

Medication History
Available upon request. Records of ART history, viral load status, and history of treatments affecting NK cell exhaustion markers and ADCC capacity.

Formulation
Cryopreserved in specialized freezing medium

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.

Storage
Maintain long-term storage in liquid nitrogen vapor phase (below -150°C), avoid temperature fluctuations above -135°C to preserve NK cell lytic activity.

Shiping
Dry Ice

Handling Notes
Perform rapid thawing at 37°C and implement slow, dropwise dilution with pre-warmed media to minimize osmotic stress and ensure optimal cell recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
5E6 cells/vial, 1E7 cells/vial

Keywords
CellRapeutics™ CD56⁺ NK Cells from Human Immunodeficiency Virus HIV Donor, CD56⁺ NK Cells, Human Immunodeficiency Virus HIV

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.