CellRapeutics™ CD56⁺ NK Cells from Scleroderma Donor (XS-0426-XU301)

Name: CellRapeutics™ CD56+ NK Cells from Scleroderma Donor
SKU: XS-0426-XU301
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Sourced from donors with Systemic Sclerosis, these CD56⁺ NK cells provide a unique window into the innate immune regulation of fibrosis. The cells are isolated to ensure maximum viability for functional assays focusing on NK-mediated inhibition of collagen synthesis or their direct cytotoxic effects on pathogenic myofibroblasts. This product is vital for understanding the transition from vascular injury to irreversible tissue scarring.

Specific Inquiry

Add to Cart

Donor Information

Product Name
CellRapeutics™ CD56⁺ NK Cells from Scleroderma Donor

Cat. No.
XS-0426-XU301

Donor Age
Middle-Aged

Donor Health
NK cells exhibit a pro-fibrotic signaling profile. These cells show unique phenotypic shifts that reflect their interaction with activated fibroblasts and their contribution to the systemic vascular and fibrotic microenvironment.

Ethnicity
Diverse backgrounds available, predominantly African American and Hispanic cohorts.

Anticoagulant
Heparin or Acid Citrate Dextrose, optimized to maintain cellular flexibility and functional metabolic state, accounting for altered rheological properties in scleroderma peripheral blood.

Additional Donor Information
Each lot features CD56⁺ NK cells from donors with Systemic Sclerosis. Profiles emphasize limited vs. diffuse involvement to study the NK cell contribution to vascular injury and fibrosis.

Clinical Profile
Skin thickening score, autoantibody profile, presence of Raynaud's phenomenon, and systemic involvement.

Additional Information

Medication History
Available upon request. Includes history of systemic immunosuppressants and antifibrotic agents, with documentation of vascular therapies that may influence peripheral NK cell counts.

Formulation
Cryopreserved in specialized freezing medium

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.

Storage
Maintain long-term storage in liquid nitrogen vapor phase (below -150°C), avoid temperature fluctuations above -135°C to preserve NK cell lytic activity.

Shiping
Dry Ice

Handling Notes
Perform rapid thawing at 37°C and implement slow, dropwise dilution with pre-warmed media to minimize osmotic stress and ensure optimal cell recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
5E6 cells/vial, 1E7 cells/vial

Keywords
CellRapeutics™ CD56⁺ NK Cells from Scleroderma Donor, CD56⁺ NK Cells, Scleroderma

Case Studies

Customer Reviews and Q&As

There are currently no customer reviews or questions for CellRapeutics™ CD56⁺ NK Cells from Scleroderma Donor (XS-0426-XU301). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

CellRapeutics™ CD56⁺ NK Cells from Scleroderma Donor (XS-0426-XU301)

Specific Inquiry

Donor Information

Additional Information

Case Studies

Customer Reviews and Q&As

Related Products

Immune Cell Products

T Cell Products

Control Cell Products

Dendritic Cell Products

PBMC Products

NK Cell Products

B Cell Products

Monocyte Products

CellRapeutics™ CD56+ NK Cells from Scleroderma Donor (XS-0426-XU301)

Specific Inquiry

Donor Information

Additional Information

Case Studies

Customer Reviews and Q&As

Related Products

Immune Cell Products

T Cell Products

Control Cell Products

Dendritic Cell Products

PBMC Products

NK Cell Products

B Cell Products

Monocyte Products

CellRapeutics™ CD56⁺ NK Cells from Scleroderma Donor (XS-0426-XU301)