CellRapeutics™ CD56⁺ NK Cells from Systemic Lupus Erythematosus Donor (XS-0426-XU300)

Name: CellRapeutics™ CD56+ NK Cells from Systemic Lupus Erythematosus Donor
SKU: XS-0426-XU300
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product features high-purity CD56⁺ NK cells derived from Systemic Lupus Erythematosus donors. These cells typically reflect the systemic interferon-alpha signature and often exhibit numerical or functional deficiencies common in lupus pathogenesis. This product is prioritized for researchers exploring the failure of NK cells to clear apoptotic debris and their contribution to the loss of B-cell tolerance through aberrant cytokine signaling.

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Donor Information

Product Name
CellRapeutics™ CD56⁺ NK Cells from Systemic Lupus Erythematosus Donor

Cat. No.
XS-0426-XU300

Donor Age
Young Adult

Donor Health
NK cells reflect a state of profound systemic immune dysregulation. They are characterized by impaired cytotoxic efficiency but enhanced interferon-mediated signaling signatures, reflecting the chronic Type I IFN environment of SLE.

Ethnicity
Primarily African American, Hispanic, and Asian backgrounds.

Anticoagulant
Acid Citrate Dextrose, prioritized to prevent complement activation and preserve NK cell subset distribution from SLE-associated lymphopenia samples.

Additional Donor Information
Each lot features CD56⁺ NK cells from donors with SLE. Profiles include SLEDAI scores and history of immunosuppressants, facilitating research into NK cell deficiency and interferon-gamma production in lupus.

Clinical Profile
ANA and anti-dsDNA titers, SLEDAI score, organ involvement, and current immunosuppressive regimen.

Additional Information

Medication History
Available upon request. Records of corticosteroids, antimalarials, and biologics that impact the type I interferon environment and NK cell function.

Formulation
Cryopreserved in specialized freezing medium

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.

Storage
Maintain long-term storage in liquid nitrogen vapor phase (below -150°C), avoid temperature fluctuations above -135°C to preserve NK cell lytic activity.

Shiping
Dry Ice

Handling Notes
Perform rapid thawing at 37°C and implement slow, dropwise dilution with pre-warmed media to minimize osmotic stress and ensure optimal cell recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
5E6 cells/vial, 1E7 cells/vial

Keywords
CellRapeutics™ CD56⁺ NK Cells from Systemic Lupus Erythematosus Donor, CD56⁺ NK Cells, Systemic Lupus Erythematosus

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

CellRapeutics™ CD56⁺ NK Cells from Systemic Lupus Erythematosus Donor (XS-0426-XU300)

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CellRapeutics™ CD56+ NK Cells from Systemic Lupus Erythematosus Donor (XS-0426-XU300)

Specific Inquiry

Donor Information

Additional Information

Case Studies

Customer Reviews and Q&As

Related Products

Immune Cell Products

B Cell Products

Monocyte Products

T Cell Products

NK Cell Products

Dendritic Cell Products

PBMC Products

Control Cell Products

Mouse Cell Products

CellRapeutics™ CD56⁺ NK Cells from Systemic Lupus Erythematosus Donor (XS-0426-XU300)