CellRapeutics™ CD19⁺ B Cells from Type 1 Diabetes Donor (XS-0426-XU9)

Name: CellRapeutics™ CD19+ B Cells from Type 1 Diabetes Donor
SKU: XS-0426-XU9
Rating: 5 (1 reviews)

Online Inquiry Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

These high-purity CD19⁺ B cells are harvested from T1D patients exhibiting autoimmune destruction of pancreatic beta cells. This product is a vital resource for deciphering the early stages of insulitis, specifically the B cell's role as a potent antigen-presenting cell that facilitates the activation of autoreactive T-lymphocytes against islet antigens.

Specific Inquiry

Add to Cart

Donor Information

Product Name
CellRapeutics™ CD19⁺ B Cells from Type 1 Diabetes Donor

Cat. No.
XS-0426-XU9

Donor Age
Pediatric, Young Adult

Donor Health
Diagnosed with Type 1 Diabetes Mellitus (T1DM). Donors exhibit clear autoimmune destruction profiles of pancreatic beta cells, often with detectable islet cell autoantibodies.

Ethnicity
Diverse backgrounds available, predominantly Caucasian.

Anticoagulant
Acid Citrate Dextrose, optimized for precise pH buffering to protect sensitive autoimmune B-cell subsets from metabolic acidosis and preserve antigen-presenting functionality.

Additional Donor Information
Each lot features CD19⁺ B cells from donors with Type 1 Diabetes. Information includes age of onset, C-peptide levels, and presence of islet-specific autoantibodies, essential for researching B-cell roles in autoimmune pancreatic beta-cell destruction.

Clinical Profile
Age of onset, presence of islet autoantibodies, daily insulin requirement, and frequency of ketoacidosis episodes.

Additional Information

Medication History
Available upon request. Primarily documents insulin replacement therapy regimens and any history of participation in clinical trials involving immunomodulatory agents to preserve beta-cell function.

Formulation
Cryopreserved in specialized freezing medium

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch undergoes rigorous testing for purity, viability, and microbial contamination.

Storage
Upon arrival, immediately transfer the vial to the liquid nitrogen.

Shiping
Dry Ice

Handling Notes
Upon thawing, it is recommended to rapidly thaw the cells in a 37°C water bath, followed by the slow addition of pre-warmed culture medium to minimize osmotic shock.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
1E7 cells/vial, 2.5E7 cells/vial

Keywords
CellRapeutics™ CD19⁺ B Cells from Type 1 Diabetes Donor, CD19⁺ B Cells, Type 1 Diabetes

Case Studies

Customer Reviews and Q&As

There are currently no customer reviews or questions for CellRapeutics™ CD19⁺ B Cells from Type 1 Diabetes Donor (XS-0426-XU9). Click the button below to contact us or submit your feedback about this product.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

CellRapeutics™ CD19⁺ B Cells from Type 1 Diabetes Donor (XS-0426-XU9)

Specific Inquiry

Donor Information

Additional Information

Case Studies

Customer Reviews and Q&As

Related Products

Immune Cell Products

T Cell Products

Dendritic Cell Products

PBMC Products

B Cell Products

NK Cell Products

Control Cell Products

Mouse Cell Products

Stem Cell Products

Monocyte Products

CellRapeutics™ CD19+ B Cells from Type 1 Diabetes Donor (XS-0426-XU9)

Specific Inquiry

Donor Information

Additional Information

Case Studies

Customer Reviews and Q&As

Related Products

Immune Cell Products

T Cell Products

Dendritic Cell Products

PBMC Products

B Cell Products

NK Cell Products

Control Cell Products

Mouse Cell Products

Stem Cell Products

Monocyte Products

CellRapeutics™ CD19⁺ B Cells from Type 1 Diabetes Donor (XS-0426-XU9)