CellRapeutics™ Leukopak from Gout Donor (XS-0426-XU239)

Name: CellRapeutics™ Leukopak from Gout Donor
SKU: XS-0426-XU239
Rating: 5 (1 reviews)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Harvested from donors with confirmed gouty arthritis, this Leukopak captures the cellular mediators of the IL-1β driven autoinflammatory response. The population is rich in monocytes and neutrophils primed for inflammasome activation in response to monosodium urate crystals. This product is prioritized for researchers studying acute crystal-induced inflammation and the systemic transition from acute gouty flares to chronic tophaceous disease.

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Donor Information

Product Name
CellRapeutics™ Leukopak from Gout Donor

Cat. No.
XS-0426-XU239

Donor Age
Middle-Aged, Senior

Donor Health
Donors exhibit episodic acute inflammation. The leukocyte profile is characterized by signs of inflammasome-mediated priming and increased responsiveness to urate-associated danger signals.

Ethnicity
Diverse backgrounds available, predominantly Pacific Islander and Asian cohorts.

Anticoagulant
Acid Citrate Dextrose or Heparin, formulated to prevent NLRP3 inflammasome pre-activation by stabilizing plasma microenvironment during leukapheresis.

Additional Donor Information
Each lot features a Leukopak from donors with clinically diagnosed gout. Profiles include serum uric acid levels and history of tophi or acute flares, ideal for studying NLRP3 inflammasome activation and monocyte-to-macrophage differentiation.

Clinical Profile
Frequency of acute flare-ups, presence of tophi, and history of urate-lowering therapy.

Additional Information

Medication History
Available upon request. Records of urate-lowering therapy, colchicine, and history of NSAID use for acute flare management.

Formulation
Cryopreserved or Fresh options available.

Cell Purity
>90%

Cell Viability
>90%

Mycoplasma Testing
Negative

Sterility Testing
Negative

Genetic Stability Testing
The donor cells maintain their native genetic profile, exhibiting no karyotypic abnormalities or chromosomal instabilities typically associated with prolonged ex vivo expansion.

Application
Drug Discovery, Immuno-oncology Research

Research Use Only
RUO

Quality Control
Each product batch is strictly validated for high cellular viability, specific immune cell counts, and pathogen-free safety, ensuring consistent clinical phenotypes and ethical compliance for advanced immunological research.

Storage
Store fresh Leukopaks at 2°C to 8°C for immediate use, cryopreserved samples must be kept in liquid nitrogen vapor phase below -150°C.

Shiping
Dry Ice

Handling Notes
Process fresh cells within 48 hours or perform rapid thawing of cryovials in a 37°C water bath followed by gradual dilution to maximize recovery.

Warnings
Treat as potentially biohazardous human-derived material and handle strictly under BSL-2 guidelines using appropriate personal protective equipment.

Size
Full Bag, Half Bag

Keywords
CellRapeutics™ Leukopak from Gout Donor, Leukopak, Gout

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.