The vector of anti-CLDN6 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CLDN6. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CLDN6 antibody linked to CD3ζ signaling domain. And the vector product was designed for the treatment of ovarian cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC728||Lenti-CLDN6 CAR (scFv-41BB-CD3ζ, h27.108) Viral Particle|
|CAR-LC257||Anti-CLDN6 (h27.108) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC729||Lenti-CLDN6 CAR (scFv-41BB-CD3ζ, h27.204v2) Viral Particle|
|CAR-LC258||Anti-CLDN6 (h27.204v2) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-LC192||Anti-CLDN6 h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC670||Lenti-CLDN6 CAR (scFv-CD28-41BB-CD3ζ) Viral Particle|
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