The vector of anti-EGFRvA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human EGFRvA. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGFRvA antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of Hepatocellular carcinoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ081||Anti-EGFRvIII (131) h(CD3ζ) CAR, pCDCAR1|
|CAR-MZ080||Anti-EGFRvIII (Y10) h(OX40-CD3ζ) CAR, pCDCAR1|
|CAR-MZ009||Anti-EGFR (Nimotuzumab) h(CD3ζ) CAR, pCDCAR1|
|CAR-MZ140||Anti-EGFRvIII (MR1.1) h(CD28-CD3ζ) CAR, pCDCAR1|
|CAR-T-2-M315-2G||Anti-EGFRvIII scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|CAR-MZ066||Anti-EGFRvIII (3C10) h(CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC836||Lenti-EGFRvIII CAR (scFv-CD3ζ, MR1.1) Viral Particle|
|CAR-MZ010||Anti-EGFR (Nimotuzumab) h(CD28-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC194||Lenti-EGFR CAR (scFv-CD28-CD3ζ) Viral Particle|
|CAR-MZ073||Anti-EGFRvIII (MR-1) h(CD28-OX40-CD3ζ) CAR, pCDCAR1|
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