The vector of anti-EGFRvIII/EGFR chimeric antigen receptor (CAR) is constructed for the engineering of NK cells to target human EGFRvIII/EGFR. The NK cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGFRvIII/EGFR antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of Glioblastomas (GBM).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC586||Lenti-EGFR CAR (scFv-CD28-CD3ζ, 806) Viral Particle|
|VP-CAR-LC197||Lenti-EGFRvIII CAR (scFv-CD28, RAbDMvIII) Viral Particle|
|CAR-MZ070||Anti-EGFRvIII (MR-1) h(CD3ζ) CAR, pCDCAR1|
|CAR-T-3-M315-2XZ||Anti-EGFRvIII scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1|
|CAR-MZ074||Anti-EGFRvIII (L8A4) h(CD28-CD3ζ) CAR, pCDCAR1|
|CAR-MZ165||Anti-EGFR (R1) h(CD28-CD3ζ) CAR, Pcdcar1|
|VP-CAR-LC739||Lenti-EGFR CAR (scFv-41BB-CD3ζ, Cetuximab) Viral Particle|
|VP-CAR-LC588||Lenti-EGFR CAR (scFv-CD28-41BB-CD3ζ, 806) Viral Particle|
|CAR-MZ190||Anti-EGFRvA (2D3) h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|CAR-MZ068||Anti-EGFRvIII (3C10) h(OX40-CD3ζ) CAR, pCDCAR1|
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