The vector of anti-EGFRvIII chimeric antigen receptor (CAR) is constructed for the engineering of NK cells to target human EGFRvIII. The NK cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGFRvIII antibody linked to and CD3ζ signaling domains. And the vector product was designed for the treatment of Glioblastomas (GBM).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|OAdCmodV-YX0612||Oncolytic Adenovirus (Capsid modified Ad5, pCMV-Δ55k, Anti-EGFR-11), Viral particle|
|OAdCmodV-YX0690||Oncolytic Adenovirus (Capsid modified Ad5, phTERT-Δ19k, Anti-EGFR-5), Viral particle|
|CAR-MZ189||Anti-EGFRvA (2D3) h(41BB-CD3ζ) CAR, pCDCAR1|
|CAR-LC098||Anti-EGFR (806) h(CD28-CD3ζ) CAR, pCDCAR1|
|OAdCmodV-YX0643||Oncolytic Adenovirus (Capsid modified Ad5, pCMV-Δ19k, Anti-EGFR-6), Viral particle|
|VP-CAR-LC857||Lenti-EGFR CAR (scFv-CD3ζ, R1) Viral Particle|
|VP-CAR-LC878||Lenti-EGFRvA CAR (scFv-CD28-CD3ζ, 2D3) Viral Particle|
|CAR-LC127||Anti-EGFR (Cetuximab) h(41BB-CD3ζ) CAR, pCDCAR1|
|OAdCmodV-YX0640||Oncolytic Adenovirus (Capsid modified Ad5, pCMV-Δ19k, Anti-EGFR-3), Viral particle|
|CAR-T-1-L338-G||Anti-EGFR scFv h(FcεRIγ) CART, pCDCAR1|
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