The vector of anti-ErbB2 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human ErbB2. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-ErbB2 antibody linked to CD28 and FcγR signaling domains. And the vector product was designed for the treatment of ErbB2 positive cancers.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-LC188||Anti-HER2 h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC748||Lenti-ErbB2 CAR (scFv-CD28-CD3ζ, Trastuzumab) Viral Particle|
|TCR-C099Z||Murinized anti-HER2 T cell receptor (HER2-3), pCDTCR1|
|CAR-YF188||Anti-HER2 (C5) h(4-1BB-CD3ζ) CAR, pCDCAR1|
|CAR-YF232||Anti-HER2 (N29) h(CD28-CD3ζ) CAR, pCDCAR1|
|CAR-MZ135||Anti-ErbB2 (L96) h(CD28-FcγR) CAR, pCDCAR1|
|CAR-NK-2-M331-2Z||Anti-ErbB2 scFv h(CD28-CD3ζ) CARNK, pCDCAR1|
|VP-CAR-LC667||Lenti-HER2 CAR (scFv-CD28-41BB-CD3ζ) Viral Particle|
|VP-CAR-LC231||Lenti-ErbB2 CAR (scFv-CD28-41BB-CD3ζ, OTI5C4) Viral Particle|
|VP-CAR-LC224||Lenti-ErbB2 CAR (scFv-CD28-FcεRIγ, OTI5C4) Viral Particle|
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