FITC-labeled Human CD4 CAR Detection Reagent, His Tag (CARD-LX112)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. FITC-labeled Human CD4 CAR Detection Reagent, His Tag is a special detection reagent which is used to detect Human CD4 CAR related to the study of immune diseases.

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Specifications

Target
CD4

Application
FC, ELISA

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Application Notes
The optimal working dilutions should be determined by the end user.

Diseases
Autoimmune Diseases

Molecular Characterization
It contains AA Lys 26 - Trp 390 (Accession # AAH25782).

Conjugation
FITC

Size
0.2 mg

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
Human HEK293 cells

Host Species
Human

Species Reactivity
Human

Form
lyophilized

Images
Figure 1 Structure

Figure 2 Binding activity Evaluation

Target

Target Introduction
T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Target Alternative Names
CD4

UniProt ID
AAH25782

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

FITC-labeled Human CD4 CAR Detection Reagent, His Tag (CARD-LX112)

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Specifications

Target

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