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pCDCAR5 FOLH1 h(LAG3) (CAR-LC387)

The vector of anti-PSMA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human PSMA. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-PSMA antibody linked to LAG3 inhibitory signaling domains. And the vector product was designed for the treatment of prostate cancer.

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Details

  • Target
  • PSMA
  • Targeting Cell Type
  • T cell
  • Targeting Diseases
  • Prostate cancer
  • Generation
  • First
  • Vector Name
  • pCDCAR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Retroviral
  • Receptor Construction
  • scFv-LAG3

Target

  • Clone
  • HuJ593
  • Host
  • Human
  • Target Species
  • Human
  • Gene Name
  • folate hydrolase 1
  • Synonyms
  • PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; NAALAdase

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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