Anti-Bob1 T cell receptor (4G11), pCDTCR1(TCR-C014Z)

The vector of anti-Bob1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human Bob1. The T cells are genetically modified through transduction with a lentiviral vector expressing Bob1-specific T cell receptor. And the vector product was designed for the treatment of Multiple myeloma.


Details


Target
Bob1
Target Species
Human
Epitope
APAPTAVVL
Format
Codon optimized
HLA
HLA-B*0702
Targeting Diseases
Multiple myeloma
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
4G11
Antibody Host
Human

Target


Gene Name
POU class 2 associating factor 1
Official Symbol
POU2AF1
Gene ID
UniProt ID
Synonyms
BOB1; OBF1; OCAB; OBF-1; POU2AF1; POU class 2 associating factor 1
Introduction
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Carcinoma

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CONTACT US

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-097-1828

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