Anti-BZLF1 T cell receptor (CA5), pCDTCR1(TCR-C018Z)

The vector of anti-BZLF1 T cell receptor (TCR) is constructed for the engineering of T cell to target EBV BZLF1. The T cells are genetically modified through transduction with a lentiviral vector expressing BZLF1-specific T cell receptor. And the vector product was designed for the treatment of EBV infection.


Details


Target
BZLF1
Target Species
EBV
Epitope
LPEPLPQGQLTAY
Format
Codon optimized
HLA
HLA B*3505
Targeting Diseases
EBV infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
CA5
Antibody Host
Human

Target


Gene Name
Trans-activator protein BZLF1
Official Symbol
BZLF1
UniProt ID
Synonyms
BZLF1; Trans-activator protein BZLF1; EB1
Introduction
Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1).

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-097-1828

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