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Human CD138 CAR Detection Reagent, His Tag (CARD-LX042)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. Human CD138 CAR Detection Reagent, His Tag is a special detection reagent which carries a polyhistidine tag at the C-terminus, and is used to detect human CD138 CAR related to the study of Multiple myeloma.

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Specifications

  • Target
  • CD138
  • Application
  • ELISA, FC
  • Purity
  • >90%
  • Endotoxin Level
  • Less than 1.0 EU per μg by the LAL method.
  • Storage
  • For long term storage, the product should be stored at lyophilized state at -52°C or lower.
    Please avoid repeated freeze-thaw cycles.
  • Application Notes
  • The optimal working dilutions should be determined by the end user.
  • Diseases
  • Multiple myeloma
  • Molecular Characterization
  • It contains AA Gln 23 - Gly 254 (Accession # AAH08765).
  • Conjugation
  • Unconjugated
  • Tag
  • His Tag
  • Size
  • 0.1 mg
  • Formulation
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
  • Expression
  • Human HEK293 cells
  • Host Species
  • Human
  • Species Reactivity
  • Human
  • Form
  • Lyophilized
  • Images
  • Figure 1 Structure

Target

  • Target Introduction
  • Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
  • Target Alternative Names
  • syndecan 1
  • Entrez Gene ID
  • 6382

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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