Anti-EBNA3A T cell receptor (CF3), pCDTCR1(TCR-C051Z)

The vector of anti-EBNA3A T cell receptor (TCR) is constructed for the engineering of T cell to target EBV EBNA3A. The T cells are genetically modified through transduction with a lentiviral vector expressing EBNA3A-specific T cell receptor. And the vector product was designed for the treatment of EBV infection.


Details


Target
EBNA3A
Target Species
EBV
Epitope
FLRGRAYGL
Format
Single-chain
HLA
HLA-B*0802
Targeting Diseases
EBV infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
CF3
Antibody Host
Human

Target


Gene Name
Epstein-Barr nuclear antigen 3A
Official Symbol
EBNA3A
Gene ID
Synonyms
EBNA3A; Epstein-Barr nuclear antigen 3A
Introduction
Epstein-Barr virus (EBV), a human gammaherpesvirus, can cause lymphocyte-proliferative diseases in immune-deficient people and is also etiologically associated with Burkitt's lymphoma, Hodgkin's disease, other B- and T-cell lymphomas, anaplastic nasopharyngeal carcinoma, and a small fraction of gastric carcinomas. Epstein-Barr Virus Nuclear Protein EBNA3A Is Critical for Maintaining Lymphoblastoid Cell Line Growth.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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