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Anti-gag p17 T cell receptor, pCDTCR1 (TCR-C071Z)

The vector of anti-gag p17 T cell receptor (TCR) is constructed for the engineering of T cell to target HIV-1 gag p17. The T cells are genetically modified through transduction with a lentiviral vector expressing gag p17-specific T cell receptor. And the vector product was designed for the treatment of HIV-1 infection.

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Details

  • Target
  • gag p17
  • Target Species
  • HIV-1
  • Epitope
  • SLYNTVATL
  • Format
  • Non-modified
  • Allele
  • HLA-A*0201
  • Targeting Diseases
  • HIV-1 infection
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Host Species
  • Human

Target

  • Official Symbol
  • gag
  • Introduction
  • Matrix protein p17: Targets the polyprotein to the plasma membrane via a multipartite membrane-binding signal, that includes its myristoylated N-terminus. Matrix protein is part of the pre-integration complex. Implicated in the release from host cell mediated by Vpu. Binds to RNA

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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