Anti-gag p17 T cell receptor (C-4), pCDTCR1(TCR-C070Z)

The vector of anti-gag p17 T cell receptor (TCR) is constructed for the engineering of T cell to target HIV-1 gag p17. The T cells are genetically modified through transduction with a lentiviral vector expressing gag p17-specific T cell receptor. And the vector product was designed for the treatment of HIV infection.


Details


Target
gag p17
Target Species
HIV-1
Epitope
SLYNTVATL
Format
Non-modified
HLA
HLA-A2
Targeting Diseases
HIV infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
C-4
Antibody Host
Human

Target


Gene Name
gag protein
Official Symbol
gag
Gene ID
UniProt ID
Synonyms
FrMLVgp1; gag; gag protein; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; viral infection
Introduction
Matrix protein p17: Targets the polyprotein to the plasma membrane via a multipartite membrane-binding signal, that includes its myristoylated N-terminus. Matrix protein is part of the pre-integration complex. Implicated in the release from host cell mediated by Vpu. Binds to RNA

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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