Anti-gag T cell receptor (HIV-B60-SL9), pCDTCR1(TCR-L331)

The vector of anti-gag T cell receptor (TCR) is constructed for the engineering of T cell to target HIV-l gag. The T cells are genetically modified through transduction with a lentiviral vector expressing gag-specific T cell receptor. And the vector product was designed for the treatment of HIV infection.


Details


Target
gag
Target Species
HIV-l
Epitope
SEGATPQDL
Format
Non-modified
HLA
HLA-B60
Targeting Diseases
HIV infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
HIV-B60-SL9
Antibody Host
Human

Target


Gene Name
gag protein
Official Symbol
GAG
Gene ID
UniProt ID
Synonyms
FrMLVgp1; gag; gag protein; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; viral infection
Introduction
Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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