1. Home
  2. MART-1
  3. Human anti-MART1 T cell receptor (2C2), pCDTCR1

Anti-MART1 T cell receptor (2C2), pCDTCR1(TCR-C143Z)

DatasheetDatasheet

Online Inquiry

The vector of anti-MART1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human MART1. The T cells are genetically modified through transduction with a lentiviral vector expressing MART1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.

Details

Target
MART-1
Target Species
Human
Epitope
EAAGIGILTV
Format
Codon optimized
HLA
HLA-A*0201
Targeting Diseases
Melanoma
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
2C2
Antibody Host
Human

Target

Gene Name
MLANA
Official Symbol
MLANA
Gene ID
2315
UniProt ID
Q16655
Synonyms
DMF5; MLANA; MART1; MART-1; metastatic melanoma; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; Melan-A
Introduction
Protein melan-A also known as melanoma antigen recognized by T cells 1 or MART-1 is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

Cat# Description
CAR-T-3-M310-2XZ Anti-MART-1(DMF5) scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1
TCR-C145Z Human anti-MART1 T cell receptor (α24β17), pCDTCR1
TCR-C142Z Human anti-MART1 T cell receptor (Codon optimized) (DMF4), pCDTCR1
VP-CAR-LC336 Lenti-MART-1(DMF5) CAR (scFv-CD8-CD3ζ, Melan-A) Viral Particle
TCR-L065 Human anti-MLANA (AAGIGILTV) T Cell Receptor, pMX-IRES-GFP
VP-CAR-LC340 Lenti-MART-1(DMF5) CAR (scFv-CD28-OX40-CD3ζ, Melan-A) Viral Particle
TCR-L072 Human anti-MLANA (ELAGIGILTV) T Cell Receptor, pLXSN
TCR-L071Z Human anti-melan-A T cell receptor, pCDTCR1
VP-TCR-C293 Lenti-MART-1 T cell receptor (Codon optimized) (DMF4) Viral Particle
VP-TCR-C299 Lenti-melan-A T cell receptor (SW-M1-9) Viral Particle

Carcinoma Kits for CARs/TCRs Development 

Online Inquiry

Name:
* Phone:
*E-mail Address:
*Service & Products Interested:
Project Description:
*Verification Code:
Please input "biolabs"(case insensitive) as verification code.
CB Promise
CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select your country or region:

Australia
australia

FOLLOW US ON

Copyright © 2007 - 2018 Creative Biolabs. All Rights Reserved