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Anti-NS3 T cell receptor (I2B11), pCDTCR1 (TCR-L354)

The vector of anti-NS3 T cell receptor (TCR) is constructed for the engineering of T cell to target HCV NS3. The T cells are genetically modified through transduction with a lentiviral vector expressing NS3-specific T cell receptor. And the vector product was designed for the treatment of HCV infection.

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Details

  • Target
  • NS3
  • Target Species
  • HCV
  • Epitope
  • aa 1073-1081
  • Format
  • Non-modified
  • HLA
  • HLA-A2
  • Targeting Diseases
  • HCV infection
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • I2B11
  • Antibody Host
  • Human

Target

  • Official Symbol
  • NS3
  • Introduction
  • Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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