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Anti-NY-ESO-1 T cell receptor (TCRCD4-NY#7), pCDTCR1(TCR-L161)

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The vector of anti-NY-ESO-1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human NY-ESO-1. The T cells are genetically modified through transduction with a lentiviral vector expressing NY-ESO-1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma, breast cancer, lung cancer, prostate cancer, thyroid cancer, ovarian cancer, or synovial cell sarcoma..

Details

Target
NY-ESO-1
Target Species
Human
Epitope
PVPGVLLKEFTVSGNILTIRLTA
Format
Non-modified
HLA
HLA-DRB1*1101
Targeting Diseases
Melanoma, breast cancer, lung cancer, prostate cancer, thyroid cancer, ovarian cancer, or synovial cell sarcoma.
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
TCRCD4-NY#7
Antibody Host
Human

Target

Gene Name
cancer/testis antigen 1B
Official Symbol
CTAG1B
Gene ID
1485
UniProt ID
P78358
Synonyms
CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1; NY-ESO-1–positive tumors; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; ES121
Introduction
NY-ESO-1 is a human tumor antigen of the cancer/testis family. It is highly expressed in many poor-prognosis melanomas.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Tel: 44-207-097-1828

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