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Anti-survivin T cell receptor (SW-Surv-22), pCDTCR1 (TCR-L247)

The vector of anti-survivin T cell receptor (TCR) is constructed for the engineering of T cell to target Human survivin. The T cells are genetically modified through transduction with a lentiviral vector expressing survivin-specific T cell receptor. And the vector product was designed for the treatment of Non-small cell lung cancer (NSCLC) .

Details

  • Target
  • survivin
  • Target Species
  • Human
  • Epitope
  • LMLGEFLKL
  • Format
  • Non-modified
  • HLA
  • HLA-A*0201
  • Targeting Diseases
  • Non-small cell lung cancer (NSCLC)
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • SW-Surv-22
  • Antibody Host
  • Human

Target

  • Gene Name
  • Survivin
  • Official Symbol
  • Survivin
  • Synonyms
  • Survivin; baculoviral inhibitor of apoptosis repeat-containing 5; BIRC5
  • Introduction
  • Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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