Anti-Tetanus toxin T cell receptor (Pil-2/33 ), pCDTCR1(TCR-C248Z)

The vector of anti-Tetanus toxin T cell receptor (TCR) is constructed for the engineering of T cell to target Clostridium tetani Tetanus toxin. The T cells are genetically modified through transduction with a lentiviral vector expressing Tetanus toxin-specific T cell receptor. And the vector product was designed for the treatment of Tetanus.


Details


Target
Tetanus toxin
Target Species
Clostridium tetani
Epitope
aa 1061-1075
Format
Non-modified
HLA
HLA-DRB1*0301
Targeting Diseases
Tetanus
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
Pil-2/33
Antibody Host
Human

Target


Gene Name
Tetanus toxin
Official Symbol
Tetanus toxin
Synonyms
Tetanus toxin; TT
Introduction
Tetanus toxin is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. It is also called spasmogenic toxin, or TeNT.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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