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Anti-Tetanus toxin T cell receptor (Pil-36 ), pCDTCR1 (TCR-C247Z)

The vector of anti-Tetanus toxin T cell receptor (TCR) is constructed for the engineering of T cell to target Clostridium tetani Tetanus toxin. The T cells are genetically modified through transduction with a lentiviral vector expressing Tetanus toxin-specific T cell receptor. And the vector product was designed for the treatment of Tetanus.

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Details

  • Target
  • Tetanus toxin
  • Target Species
  • Clostridium tetani
  • Epitope
  • aa 1272-1284
  • Format
  • Non-modified
  • HLA
  • HLA-DRB1*0301
  • Targeting Diseases
  • Tetanus
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral
  • Antibody Clone
  • Pil-36
  • Antibody Host
  • Human

Target

  • Official Symbol
  • Tetanus toxin
  • Introduction
  • Tetanus toxin is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. It is also called spasmogenic toxin, or TeNT.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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