The vector of anti-L1 cell adhesion molecule(L1-CAM) chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human L1 cell adhesion molecule(L1-CAM). The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-L1 cell adhesion molecule(L1-CAM) antibody linked to CD3ζ signaling domains. And the vector product was designed for the treatment of L1-CAM+ ovarian cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-T-2-M307-2G||Anti-CD171 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|CAR-T-1-M307-Z||Anti-CD171 scFv h(CD3ζ) CART, pCDCAR1|
|VP-CAR-LC887||Lenti-L1 cell adhesion molecule(L1-CAM) CAR (scFv-41BB-CD3ζ, CE7) Viral Particle|
|VP-CAR-LC314||Lenti-CD171 CAR (scFv-b2c-CD3ζ, CE7) Viral Particle|
|CAR-MZ197||Anti-L1-CAM (CE7) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC313||Lenti-CD171 CAR (scFv-41BB-CD3ζ, CE7) Viral Particle|
|CAR-T-2-M307-CZ||Anti-CD171 scFv h(b2c-CD3ζ) CART, pCDCAR1|
|CAR-T-3-M307-2XZ||Anti-CD171 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC305||Lenti-CD171 CAR (scFv-CD28, CE7) Viral Particle|
|CAR-T-2-M307-4Z||Anti-CD171 scFv h(CD4-CD3ζ) CART, pCDCAR1|
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