Lenti-α-FITC CAR (scFv-28BBζ)-VP(VP-CAR-LC511)
The ready-to-use lentiviral particles of Lenti-α-FITC CAR (scFv-28BBζ)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv-CD28-41BB-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.
Specifications
Type of Therapeutics
Chimeric Antigen Receptor
Expression Cassette
scFv-CD28-41BB-CD3ζ
Packaging System
Lentivirus
Targeting Diseases
Various cancer cells stained with FITC-labeled antibodies
Target
Introduction
Fluorescein isothiocyanate (FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. FITC is the original fluorescein molecule functionalized with an isothiocyanate reactive group (-N=C=S), replacing a hydrogen atom on the bottom ring of the structure. This derivative is reactive towards nucleophiles including amine and sulfhydryl groups on proteins.
Alternative Names
FITC; FI; fluorescein isothyocianate; fluorescyl antibody; CD28; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; scFv; 67A4
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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Others
Kits for CARs/TCRs Development 
Datasheet
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