Lenti-CD276 CAR (scFv-28, m851)-VP(VP-CAR-LC85)
The ready-to-use lentiviral particles of Lenti-CD276 CAR (scFv-28, m851)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (m851)-CD28 packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.
Specifications
Type of Therapeutics
Chimeric Antigen Receptor
Expression Cassette
scFv (m851)-CD28
Packaging System
Lentivirus
Targeting Diseases
Chronic lymphocytic leukemia (CLL)
Target
Introduction
CD276 (CD276 Molecule) is a Protein Coding gene. Diseases associated with CD276 include Neuroblastoma and Acute Cervicitis. Among its related pathways are T Cell Co-Signaling Pathway: Ligand-Receptor Interactions and NF-kappaB Signaling. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is LOC102723996.
Alternative Names
CD276 Molecule; CD276 Antigen; Costimulatory Molecule; B7 Homolog 3; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2;
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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LeukemiaOthers
Kits for CARs/TCRs Development 
Datasheet
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