Lenti-CD37 CAR (scFv-28OXζ, G28-1)-VP(VP-CAR-LC120)

The ready-to-use lentiviral particles of Lenti-CD37 CAR (scFv-28OXζ, G28-1)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (G28-1)-CD28-OX40-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
CD37
Expression Cassette
scFv (G28-1)-CD28-OX40-CD3ζ
Clone
G28-1
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Systemic lupus erythematosus (SLE)

Target


Introduction
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37ζ; Systemic Lupus Erythematosus; SLE; scFv; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; G28-1; CD28
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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