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Lenti-CD4 CAR (scFv-28BBζ, Hu5A8)-VP (VP-CAR-LC722)

The ready-to-use lentiviral particles of Lenti-CD4 CAR (scFv-28BBζ, Hu5A8)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (Hu5A8)-CD28-41BB-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

Specifications

  • Type of Therapeutics
  • Chimeric Antigen Receptor
  • Target
  • CD4
  • Expression Cassette
  • scFv (Hu5A8)-CD28-41BB-CD3ζ
  • Clone
  • Hu5A8
  • Promotor
  • EF1a
  • Packaging System
  • Lentivirus
  • Packaging Cell
  • 293T
  • Targeting Diseases
  • Non-Hodgkin lymphomas

Target

  • Introduction
  • CD4 (CD4 Molecule) is a Protein Coding gene. Diseases associated with CD4 include Okt4 Epitope Deficiency and Pilonidal Sinus. Among its related pathways are G-protein signaling N-RAS regulation pathway and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding.
  • Alternative Names
  • T-cell surface glycoprotein CD4; CD4 antigen; T-cell surface antigen T4/Leu-3

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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