Lenti-CD56 CAR (scFv-28BBζ, N901)-VP(VP-CAR-LC399)

The ready-to-use lentiviral particles of Lenti-CD56 CAR (scFv-28BBζ, N901)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (N901)-CD28-41BB-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
CD56
Expression Cassette
scFv (N901)-CD28-41BB-CD3ζ
Clone
N901
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Relapsed refractory myeloma

Target


Introduction
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Alternative Names
NCAM1; neural cell adhesion molecule 1; CD56; NCAM; MSK39; relapsed refractory myeloma; myeloma; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; N901
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Carcinoma

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-097-1828

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