1. Home
  2. HBV
  3. Lenti-HBV CAR (scFv-CD3ζ, S 26) Viral Particle

Lenti-HBV CAR (scFv-ζ, S 26)-VP(VP-CAR-LC451)

DatasheetDatasheet

Online Inquiry

The ready-to-use lentiviral particles of Lenti-HBV CAR (scFv-ζ, S 26)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (S 26)-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

Specifications

Type of Therapeutics
Chimeric Antigen Receptor
Target
HBV
Expression Cassette
scFv (S26)-CD3ζ
Clone
S 26
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Cirrhosis; hepatocellular carcinoma (HCC); liver cancer

Target

Introduction
The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane (Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.
Alternative Names
HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; HBVgp2; large S protein; pre-S1/pre-S2/S; L glycoprotein; L-HBsAG; LHB; large surface protein; major surface antigen; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; S 26
Gene ID
944569

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products

Cat# Description
VP-CAR-LC454 Lenti-HBV CAR (scFv-CD4-FcεRIγ, S 26) Viral Particle
VP-CAR-LC455 Lenti-HBV CAR (scFv-CD4-CD3ζ, S 26) Viral Particle
CAR-T-3-M319-2XZ Anti-HBV S protein scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1
VP-CAR-LC449 Lenti-HBV CAR (scFv-CD28, S 26) Viral Particle
CAR-T-2-M319-4Z Anti-HBV S protein scFv h(CD4-CD3ζ) CART, pCDCAR1
VP-CAR-LC459 Lenti-HBV CAR (scFv-CD28-41BB-CD3ζ, S 26) Viral Particle
VP-CAR-LC452 Lenti-HBV CAR (scFv-CD28-FcεRIγ, S 26) Viral Particle
CAR-T-2-M319-2G Anti-HBV S protein scFv h(CD28-FcεRIγ) CART, pCDCAR1
CAR-T-2-M319-CZ Anti-HBV S protein scFv h(b2c-CD3ζ) CART, pCDCAR1
CAR-T-3-M319-2BZ Anti-HBV S protein scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1

Blastoma Kits for CARs/TCRs Development 

Online Inquiry

Name:
* Phone:
*E-mail Address:
*Service & Products Interested:
Project Description:
*Verification Code:
Please input "biolabs"(case insensitive) as verification code.
CB Promise
CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON

Copyright © 2007 - 2018 Creative Biolabs. All Rights Reserved