Lenti-HSP70 CAR (scFv-BBζ, cmHsp70.1)-VP(VP-CAR-LC726)

The ready-to-use lentiviral particles of Lenti-HSP70 CAR (scFv-BBζ, cmHsp70.1)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (cmHsp70.1)-41BB-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.


Specifications


Type of Therapeutics
Chimeric Antigen Receptor
Target
HSP70
Expression Cassette
scFv (cmHsp70.1)-41BB-CD3ζ
Clone
cmHsp70.1
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Head-and-neck cancer

Target


Introduction
The 70 kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress.
Alternative Names
HSPA4; heat shock protein family A (Hsp70) member 4; RY; APG-2; HSPH2; hsp70; hsp70RY; HEL-S-5a; HS24/P52
Gene ID

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-097-1828

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