Lenti-HSP70 CAR (scFv-BBζ, Humanized cmHsp70.1)-VP(VP-CAR-LC727)
The ready-to-use lentiviral particles of Lenti-HSP70 CAR (scFv-BBζ, Humanized cmHsp70.1)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (Humanized cmHsp70.1)-41BB-CD3ζ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.
Type of Therapeutics
Chimeric Antigen Receptor
The 70 kilodalton heat shock proteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress.
HSPA4; heat shock protein family A (Hsp70) member 4; RY; APG-2; HSPH2; hsp70; hsp70RY; HEL-S-5a; HS24/P52
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.