Lenti-TAG-72 CAR (scFv-28εRIγ, CC49)-VP(VP-CAR-LC464)
The ready-to-use lentiviral particles of Lenti-TAG-72 CAR (scFv-28εRIγ, CC49)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (CC49)-CD28-FcεRIγ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.
Specifications
Type of Therapeutics
Chimeric Antigen Receptor
Expression Cassette
scFv (CC49)-CD28-FcεRIγ
Packaging System
Lentivirus
Targeting Diseases
Colon cancer
Target
Introduction
Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary,[citation needed] breast, colon, lung, and pancreatic cancers.[1][2] It is a mucin-like molecule with a molar mass of over 1000 kDa
Alternative Names
TAG-72; mucin antigen; Tumor-associated glycoprotein; Colon cancer; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; CC49
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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Carcinoma
Kits for CARs/TCRs Development 
Datasheet
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