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Lenti-TAG-72 CAR (scFv-28εRIγ, CC49)-VP(VP-CAR-LC464)

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The ready-to-use lentiviral particles of Lenti-TAG-72 CAR (scFv-28εRIγ, CC49)-VP is packaged using 3rd generation of lentiviral packaging system, in which the gene of CAR will be driven by a CMV promotor. The target gene of scFv (CC49)-CD28-FcεRIγ packaged in lentiviral particles could be used for high efficency tranduction of T cells and stably integrated expression.

Specifications

Type of Therapeutics
Chimeric Antigen Receptor
Target
TAG-72
Expression Cassette
scFv (CC49)-CD28-FcεRIγ
Clone
CC49
Promotor
CMV
Packaging System
Lentivirus
Packaging Cell
293T
Targeting Diseases
Colon cancer

Target

Introduction
Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary,[citation needed] breast, colon, lung, and pancreatic cancers.[1][2] It is a mucin-like molecule with a molar mass of over 1000 kDa
Alternative Names
TAG-72; mucin antigen; Tumor-associated glycoprotein; Colon cancer; scFv; FcεRIγ; Chimeric antigen receptor; T cell; Retrovirus; CARs; Lentivirus; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; CC49

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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VP-CAR-LC468 Lenti-TAG-72 CAR (scFv-CD8-CD3ζ, CC49) Viral Particle
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VP-CAR-LC462 Lenti-TAG-72 CAR (scFv-FcεRIγ, CC49) Viral Particle
CAR-T-2-M551-2G Anti-TAG-72 VHH h(CD28-FcεRIγ) CAR, [T]
CAR-T-3-M551-2XZ Anti-TAG-72 VHH h(CD28-OX40-CD3ζ) CAR, [T]
CAR-T-2-M551-CZ Anti-TAG-72 VHH h(b2c-CD3ζ) CAR, [T]
CAR-T-2-M325-4Z Anti-TAG-72 scFv h(CD4-CD3ζ) CART, pCDCAR1
CAR-T-2-M551-4G Anti-TAG-72 VHH h(CD4-FcεRIγ) CAR, [T]

Carcinoma Kits for CARs/TCRs Development 

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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